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  • Vancomycin exhibits time dependent killing, which implies that maintaining trough serum concentrations above the MIC is the most important determinant of therapeutic outcome.
  • Vancomycin given as a continuous infusion avoids high peak concentrations and allows the maintenance of a steady state concentration above the MIC
  • Additional benefits of a vancomycin continuous infusion include:
    • Less nursing time required for administration
    • Random vancomycin levels can be obtained for therapeutic drug monitoring
    • Less cost of acquisition and wastage
 Dosing
 Dilution and Preparation
 Therapeutic Range
 
References:
  1. Vancomycin Dosing - CHW. 23 February 2016
  2. https://www.ncbi.nlm.nih.gov/pubmed/23172265
  3. Vancomycin Dosing for Pediatrics University Health System

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