Daily Healthy: Product Information

Mannitol

<div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"><b>Availability: <o:p></o:p></b></div><ul><li>Mannitol 10% (INFUSOL®M10)<o:p></o:p></li><li>Mannitol 20% (INFUSOL®M20)<o:p></o:p></li></ul><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"><b>Composition:<o:p></o:p></b></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">                                             <b>10%                                     20%<o:p></o:p></b></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">Mannitol                                10g                                       20g<o:p></o:p></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">Water for Injection to          100mL                                  100mL<o:p></o:p></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">Osmolarity                        550mOsm/L                       1100mOsm/L<b> <o:p></o:p></b></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"><b><br /></b></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"><b>Dosing and Administration for Diuretic:</b><br /><br /> <br /><table border="1" cellpadding="0" cellspacing="0" class="MsoTableLightGridAccent2" style="border-collapse: collapse; border: none; mso-border-alt: solid #C0504D 1.0pt; mso-border-themecolor: accent2; mso-padding-alt: 0in 5.4pt 0in 5.4pt; mso-yfti-tbllook: 1184;"> <tbody><tr style="mso-yfti-firstrow: yes; mso-yfti-irow: -1;">  <td style="border-bottom: solid #C0504D 2.25pt; border: solid #C0504D 1.0pt; mso-border-bottom-themecolor: accent2; mso-border-themecolor: accent2; padding: 0in 5.4pt 0in 5.4pt; width: 239.4pt;" valign="top" width="319"><div align="center" class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-yfti-cnfc: 5; text-align: center;"><b><span style="font-family: "cambria" , "serif"; mso-ascii-theme-font: major-latin; mso-bidi-font-family: "Times New Roman"; mso-bidi-font-weight: bold; mso-bidi-theme-font: major-bidi; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: major-latin;">Adult</span></b></div></td>  <td style="border-bottom: solid #C0504D 2.25pt; border-left: none; border-right: solid #C0504D 1.0pt; border-top: solid #C0504D 1.0pt; mso-border-bottom-themecolor: accent2; mso-border-left-alt: solid #C0504D 1.0pt; mso-border-left-themecolor: accent2; mso-border-right-themecolor: accent2; mso-border-top-themecolor: accent2; padding: 0in 5.4pt 0in 5.4pt; width: 239.4pt;" valign="top" width="319"><div align="center" class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-yfti-cnfc: 1; text-align: center;"><b><span style="font-family: "cambria" , "serif"; mso-ascii-theme-font: major-latin; mso-bidi-font-family: "Times New Roman"; mso-bidi-font-weight: bold; mso-bidi-theme-font: major-bidi; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: major-latin;">Paediatric</span></b></div></td> </tr><tr style="mso-yfti-irow: 0; mso-yfti-lastrow: yes;">  <td style="background: #EFD3D2; border-top: none; border: solid #C0504D 1.0pt; mso-background-themecolor: accent2; mso-background-themetint: 63; mso-border-themecolor: accent2; mso-border-top-alt: solid #C0504D 1.0pt; mso-border-top-themecolor: accent2; padding: 0in 5.4pt 0in 5.4pt; width: 239.4pt;" valign="top" width="319"><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 68;"><b style="mso-bidi-font-weight: normal;"><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">Dose<span style="mso-bidi-font-weight: bold;">: </span></span></b><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">50-100 gram of Mannitol  </span></div><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 68;"><br /></div><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 68;"><b style="mso-bidi-font-weight: normal;"><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">Administration</span></b><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">: rate adjusted to maintain urine flow of at least 30-50mL per hour<b>.</b></span></div><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-yfti-cnfc: 68;"><br /></div></td>  <td style="background: #EFD3D2; border-bottom: solid #C0504D 1.0pt; border-left: none; border-right: solid #C0504D 1.0pt; border-top: none; mso-background-themecolor: accent2; mso-background-themetint: 63; mso-border-bottom-themecolor: accent2; mso-border-left-alt: solid #C0504D 1.0pt; mso-border-left-themecolor: accent2; mso-border-right-themecolor: accent2; mso-border-top-alt: solid #C0504D 1.0pt; mso-border-top-themecolor: accent2; padding: 0in 5.4pt 0in 5.4pt; width: 239.4pt;" valign="top" width="319"><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 64;"><b><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">Dose</span></b><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">: 0.25-2g/kg</span></div><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 64;"><br /></div><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 64;"><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"><span style="mso-spacerun: yes;"> </span><b>Administration</b>: 2-6 hours</span></div><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-yfti-cnfc: 64;"><br /></div></td> </tr></tbody></table></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"><b>Dosing and Administration for Cerebral Oedema or Elevated Intracranial Bleeding or Glaucoma:</b><br /><br /><b> <table border="1" cellpadding="0" cellspacing="0" class="MsoTableLightGridAccent2" style="border-collapse: collapse; border: none; mso-border-alt: solid #C0504D 1.0pt; mso-border-themecolor: accent2; mso-padding-alt: 0in 5.4pt 0in 5.4pt; mso-yfti-tbllook: 1184;"> <tbody><tr style="mso-yfti-firstrow: yes; mso-yfti-irow: -1;">  <td style="border-bottom: solid #C0504D 2.25pt; border: solid #C0504D 1.0pt; mso-border-bottom-themecolor: accent2; mso-border-themecolor: accent2; padding: 0in 5.4pt 0in 5.4pt; width: 239.4pt;" valign="top" width="319"><div align="center" class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-yfti-cnfc: 5; text-align: center;"><b><span style="font-family: "cambria" , "serif"; mso-ascii-theme-font: major-latin; mso-bidi-font-family: "Times New Roman"; mso-bidi-font-weight: bold; mso-bidi-theme-font: major-bidi; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: major-latin;">Adult</span></b></div></td>  <td style="border-bottom: solid #C0504D 2.25pt; border-left: none; border-right: solid #C0504D 1.0pt; border-top: solid #C0504D 1.0pt; mso-border-bottom-themecolor: accent2; mso-border-left-alt: solid #C0504D 1.0pt; mso-border-left-themecolor: accent2; mso-border-right-themecolor: accent2; mso-border-top-themecolor: accent2; padding: 0in 5.4pt 0in 5.4pt; width: 239.4pt;" valign="top" width="319"><div align="center" class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-yfti-cnfc: 1; text-align: center;"><b><span style="font-family: "cambria" , "serif"; mso-ascii-theme-font: major-latin; mso-bidi-font-family: "Times New Roman"; mso-bidi-font-weight: bold; mso-bidi-theme-font: major-bidi; mso-fareast-font-family: "Times New Roman"; mso-fareast-theme-font: major-fareast; mso-hansi-theme-font: major-latin;">Paediatric</span></b></div></td> </tr><tr style="mso-yfti-irow: 0; mso-yfti-lastrow: yes;">  <td style="background: #EFD3D2; border-top: none; border: solid #C0504D 1.0pt; mso-background-themecolor: accent2; mso-background-themetint: 63; mso-border-themecolor: accent2; mso-border-top-alt: solid #C0504D 1.0pt; mso-border-top-themecolor: accent2; padding: 0in 5.4pt 0in 5.4pt; width: 239.4pt;" valign="top" width="319"><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 68;"><b style="mso-bidi-font-weight: normal;"><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">Dose</span></b><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">: 0.25-2g/kg</span></div><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 68;"><br /></div><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 68;"><b style="mso-bidi-font-weight: normal;"><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">Administration</span></b><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">: 30 to 60 minutes</span></div><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-yfti-cnfc: 68;"><br /></div></td>  <td style="background: #EFD3D2; border-bottom: solid #C0504D 1.0pt; border-left: none; border-right: solid #C0504D 1.0pt; border-top: none; mso-background-themecolor: accent2; mso-background-themetint: 63; mso-border-bottom-themecolor: accent2; mso-border-left-alt: solid #C0504D 1.0pt; mso-border-left-themecolor: accent2; mso-border-right-themecolor: accent2; mso-border-top-alt: solid #C0504D 1.0pt; mso-border-top-themecolor: accent2; padding: 0in 5.4pt 0in 5.4pt; width: 239.4pt;" valign="top" width="319"><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 64;"><b><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">Dose</span></b><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">: 1-2g/kg</span></div><div class="MsoNormal" style="line-height: normal; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; mso-yfti-cnfc: 64;"><br /></div><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0in; mso-yfti-cnfc: 64;"><span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;"><span style="mso-spacerun: yes;"> </span><b>Administration</b>:</span> <span style="font-family: "times new roman" , "serif"; font-size: 12.0pt;">30 to 60 minutes </span></div></td> </tr></tbody></table> </b><br /></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"><b>References:</b><o:p></o:p></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">1. INFUSOL®M10 and M20 product Information<o:p></o:p></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">2. <a href="http://www.rxlist.com/mannitol-iv-drug.htm">http://www.rxlist.com/mannitol-iv-drug.htm</a><o:p></o:p></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">3. Micromedex<o:p></o:p></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">4. Lexicomp<o:p></o:p></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;"></div><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0in;">5. Formulari Ubat KKM, March 2016.<o:p></o:p></div><div class="MsoListParagraphCxSpLast" style="margin-bottom: .0001pt; margin-bottom: 0in; mso-add-space: auto; mso-list: l0 level1 lfo1; text-indent: -.25in;"><o:p></o:p></div>

Availability: Mannitol 10% (INFUSOL®M10) Mannitol 20% (INFUSOL®M20) Composition: 10% ...

Essential Phospholipid:Livolid and Livolin Forte

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<div style="text-align: left;"><b>Availability in Hospital Keningau</b></div><ul><li>Livovid (Essential Phospholipid)</li></ul> <br /><table border="1" cellpadding="0" cellspacing="0" class="MsoTableGrid" style="border-collapse: collapse; border: none; mso-border-alt: solid windowtext .5pt; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt; mso-yfti-tbllook: 1184;"> <tbody><tr style="mso-yfti-firstrow: yes; mso-yfti-irow: 0;">  <td style="border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 113.15pt;" valign="top" width="151"><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0cm;">Content</div></td>  <td style="border: 1pt solid; padding: 0cm 5.4pt; text-align: center; width: 6cm;" valign="top" width="227"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;">Livovid (%US RDA)</div></td>  <td style="border: 1pt solid; padding: 0cm 5.4pt; text-align: center; width: 167.55pt;" valign="top" width="223"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;"><b>Livolin Forte (US RDA)*</b></div></td> </tr><tr style="mso-yfti-irow: 1;">  <td style="border-top: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 113.15pt;" valign="top" width="151"><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0cm;">Essential Phospholipid</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 6cm;" valign="top" width="227"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;">500mg</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 167.55pt;" valign="top" width="223"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;"><b>300mg</b></div></td> </tr><tr style="mso-yfti-irow: 2;">  <td style="border-top: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 113.15pt;" valign="top" width="151"><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0cm;">Vitamin B1</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 6cm;" valign="top" width="227"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;">3mg(200)</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 167.55pt;" valign="top" width="223"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;"><b>10mg(666.67)</b></div></td> </tr><tr style="mso-yfti-irow: 3;">  <td style="border-top: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 113.15pt;" valign="top" width="151"><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0cm;">Vitamin B2</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 6cm;" valign="top" width="227"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;">3mg(177)</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 167.55pt;" valign="top" width="223"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;"><b>6mg(352.94)</b></div></td> </tr><tr style="mso-yfti-irow: 4;">  <td style="border-top: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 113.15pt;" valign="top" width="151"><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0cm;">Vitamin B6</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 6cm;" valign="top" width="227"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;">3mg(150)</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 167.55pt;" valign="top" width="223"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;"><b>10mg(500)</b></div></td> </tr><tr style="mso-yfti-irow: 5;">  <td style="border-top: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 113.15pt;" valign="top" width="151"><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0cm;">Vitamin B12</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 6cm;" valign="top" width="227"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;">3mcg(100)</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 167.55pt;" valign="top" width="223"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;"><b>10mcg(500)</b></div></td> </tr><tr style="mso-yfti-irow: 6;">  <td style="border-top: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 113.15pt;" valign="top" width="151"><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0cm;">Nicotinamide</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 6cm;" valign="top" width="227"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;">15mg(75)</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 167.55pt;" valign="top" width="223"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;"><b>30mg(157.89)</b></div></td> </tr><tr style="mso-yfti-irow: 7; mso-yfti-lastrow: yes;">  <td style="border-top: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt; width: 113.15pt;" valign="top" width="151"><div class="MsoNormal" style="line-height: normal; margin-bottom: .0001pt; margin-bottom: 0cm;">Vitamin E</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 6cm;" valign="top" width="227"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;">3.3mg(10)</div></td>  <td style="border-color: -moz-use-text-color; border-style: none solid solid none; border-width: medium 1pt 1pt medium; padding: 0cm 5.4pt; text-align: center; width: 167.55pt;" valign="top" width="223"><div class="MsoNormal" style="line-height: normal; margin-bottom: 0cm;"><b>10mg(66.67)</b></div></td> </tr></tbody></table><br /> <br /><div align="center" class="MsoNormal" style="tab-stops: 88.5pt; text-align: center;">Table 1.0 Content of Livovid and Livolin Forte (*current product)</div> <b> </b><br /><b>Recommended daily dose:</b><br /><ul><li>The dosage for Livovid is 1 to 2 softgels daily or as directed by physician</li><li>The dosage of Livolin Forte is 1 capsule 3 times daily after meal or as directed by physician</li></ul><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0cm; tab-stops: 88.5pt;"><b>Content:</b></div><ul><li>The content of Essential Phospholipid in Livovid is higher than Livolin Forte while the content of vitamins are higher in Livolin Forte.</li><li>All the contents are within Tolerable Upper limit except Vitamin B1(Not established),Vitamin B12(Not established) and Nicotinamide (30-35mg/daily).</li></ul><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0cm; tab-stops: 88.5pt;"><b>Nicotinamide:</b></div><ul><li>High-dose nicotinamide should still, however, be considered as a drug with toxic potential at adult doses in excess of 3 gm/day and unsupervised use should be discouraged.</li><li>Nicotinamide has an off label use for pellagra with 100mg every 6 hours for several days and followed by 50mg every 8-12hours</li></ul><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0cm; tab-stops: 88.5pt;"><b>Vitamin B12:</b></div><ul><li>Maximum daily intake unlikely to cause adverse health effect thus no upper limit is established.</li><li>For Vitamin B12 deficiency may take up to 1000-2000mmcg daily for 1-2 weeks orally</li></ul><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0cm; tab-stops: 88.5pt;"><b>Vitamin B1:</b></div><ul><li>Large doses have been seen particularly in the treatment of Wernick Korsakoff Syndrome(10mg-1500mg daily)</li></ul><div class="MsoNormal" style="margin-bottom: .0001pt; margin-bottom: 0cm; tab-stops: 88.5pt;"><b>References:</b></div><ul><li>Livovid Product Information</li><li>Livolin Forte Product Information</li><li>http://frantzmd.info/Alternative%20Medicine/Tolerable%20Upper%20Limits.htm</li><li>https://www.consumerlab.com/RDAs/</li><li>https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional</li><li>Lexicomp</li><li>FUKKM</li></ul>