- No information available in drug information leaflets
- There are no dosage adjustments provided in the manufacturer’s labeling; use with caution
Adjustment
- 10-50 ml/min (75%)
- <10 ml/min (20-50%)
- HD : A maintenance dose may be given to patients following HD
- CAPD : 20 E 50% normal dose q 6 hr
Alternatives
- given the slow absorption and long half-life of penicillin G and published data indicating its safe use in the context of hemodialysis, the treating clinicians do decide in certain cases to proceed with penicillin G therapy at the usual dose
Reference:
- Drug Information Leaflet
- Dosing Information in Renal Impairment
- https://www.ncbi.nlm.nih.gov/pubmed/24644115
Post a Comment