Availability in Hospital Keningau:
- Diosmin 450mg & Hesperidin 50mg Tablet
Product Information:
- There is no data on the duration of Daflon as per Product Information for Chronic Venous Insufficiency(CVI).
Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS):
- No duration indicated.
- According to guidelines, Relief study which included 5052 patients that received Micronised Purified Flavonoid Fraction (MPFF) over 6 months. MPFF significantly reduced symptoms and signs, and reduced ankle oedema.
Studies:
- There is a study in which patients were given Daflon 500mg twice daily for 6 months and patients showed progressive improvement from baseline in the symptoms of CVI.
- In another study, patients were given twice daily 500mg Daflon for 1 year, there were baseline values in physician-assessed clinical symptoms (functional discomfort, cramps and evening edema), ankle and calf circumference, and patient overall assessment of symptom severity was demonstrated at each 2-months evaluation.
References:
- Antignani, P. L., & Caliumi, C. (2007). Medical Treatment of Chronic Venous Insufficiency. Vascular Disease Prevention, 4(2), 117-124.
- Management of Chronic Venous Disease:Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS)
- Daflon Product Information
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