Peripheral Thrombophlebitis
- Staph. aureus, Coagulase negative Staphylococcus, Gram negative rods
- Remove the intravenous canulla and take blood culture
- Peripheral intravenous catheters with associated pain, induration, erythema, or exudate should be removed
- Any exudate at the insertion site should be submitted for Gram staining, routine culture, and additional culture for fungi and acid-fast organisms, as indicated, when assessing immunocompromised patients
- recommend : Cloxacillin 500 mg PO q6h
Superficial Thrombophlebitis
- Superficial thrombophlebitis refers to erythema, pain, induration, and other findings of inflammation in superficial veins, usually due to infection or thrombosis
- These agents are not routinely useful in nonseptic superficial phlebitis
- choice of antibiotics should be guided by blood culture results whenever possible, but empiric therapy should at a minimum provide coverage for group A streptococci and for Staphylococcus aureus
- Ceftriaxone
- 1 to 2 g IV or IM once a day (or in equally divided doses twice a day)
Duration of therapy: 4 to 14 days
-Complicated infections: Longer therapy may be required. - Cephalexin
- Skin/Skin Structure Infections
- 250 mg PO q6hr or 500 mg PO q12hr; dosage range, 1-4 g/day in divided doses
- Cellulitis and Mastitis
- 500 mg PO q6hr; dosage range, 1-4 g/day in divided doses
References:
- http://emedicine.medscape.com/article/463256-medication#4
- Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter-Related Infection: 2009 Update by the Infectious Diseases Society of America
- National Antibiotic Guideline 2014
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